The present study contains an assessment of two regional economic communities, the Common Market for Eastern and Southern Africa and the Southern African Development Community, and the adoption of their industrialization policy frameworks and strategies as the new industrialization trajectory for member States in the region, including Malawi, Zambia and Zimbabwe. the alignment, harmonization and implementation of the COMESA and SADC industrialization strategies have been slow, the three countries have developed and adopted several IOPSs and laws and regulations relating to industrialization with explicit and implicit intentions and commitment, including fiscal resources, albeit very low, to domesticate the COMESA and SADC industrialization strategies.